Calmet D is indicated for the treatment & prevention of osteoporosis, osteomalacia, tetany, hypoparathyroidism, disorders of osteogenesis. Also used as supplement in case of inadequate intake of calcium in childhood diet. rickets, pregnancy & lactation, elderly patients. Other indications include pancreatitis, phosphate binder in chronic renal failure etc.

2 tablets daily, preferably one tablet in each morning and night.

Oral calcium can reduce the absorption of tetracycline & fluoride preparations and minimum 3 hours time should be allowed between ingestion of these medications. Thiazide diuretics reduce the renal excretion of calcium. Phenytoin, barbiturates, glucocorticoids may induce metabolism of Vitamin D. Concomitant ingestion of certain foods like spinach, cereals, milk and its derivatives may reduce the intestinal uptake of calcium.

Hypersensitivity to any of the components, hypocalcaemia resulting from overdose of Vitamin D, hyperparathyroidism, bone metastases, severe renal insufficiency, severe hypercalciuria, renal calculi etc.

Flatulence, diarrhoea, constipation, upper Gl discomfort etc. are rare manifestation. Hypercalcaemia due to prolong use has rarely been reported.

Calmet D can be given to pregnant and Iactating mothers as per recommendation of physician.

ln presence of mild hypercalciuria, careful monitoring with reduction of dose may be needed. Plasma and serum calcium level should be monitored in mild to moderate renal impairment and also in case of long term use. Patients with renal stone or with such previous history should also take precaution.

At high doses it may result in nausea, vomiting, dizziness, anorexia, abdominal cramps, headache, constipation, irritability etc. Treatment includes cessation of therapy and adequate rehydration.

· Store in cool & dry place, protect from light.
· Keep out of reach of children.