1. Stimulation of gut mobility :
a) Non-ulcer dyspepsia  b) Esophageal reflux, reflux esophagitis and gastritis
c) Diabetic gastroparesis d) Functional dyspepsia
e) Speeding barium transit in 'follow-through' radiological studies 
2. Prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radio therapy and anti-parkinsonism therapy 
3. In the prophylactic treatment of migraine

EMIDOM tablet should be taken 15-30 minutes before meal 
In case of acute nausea and vomiting the recommended oral dose 
Adults: 10-20 mg (1-2 EMIDOM  Tablet or 10-20 ml EMIDOM  Suspension) every 4-8 hours daily.
Children: 2- 4 ml EMIDOM Suspension/10 kg or 0.4- 0.8 ml EMIDOM Drops / 10 kg body weight every 4-8 hours daily.
In case of functional dyspepsia
Adults: 10-20 mg (1-2 EMIDOM Tablet or 10-20 ml EMIDOM Suspension) 3 times daily orally before meal and at night.
Children: Not recommended.
For acute nausea, vomiting and functional dyspepsia, maximum period of treatment is 12 weeks.

Domperidone may reduce the risk of hypoprolactinemic effect of bromocriptine and cabergoline. The action of Domperidone on GI function may be antagonized by antimuscarinics and opioid analgesics.

Domperidone is contraindicated in patients having known hypersensitivity to this drug and in case of neonates.

Domperidone may produce hyperprolactinemia (1.3%). This may result in galactorrhea, gynaecomastia (breast enlargement), soreness and reduced libido. Dry mouth (1.9%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhoea (0.2%), skin rash and itching (0.1%) may occur during treatment with Domperidone. Extra-pyramidal reactions are seen in 0.25% of patients in clinical studies.

Pregnant women: The safety of Domperidone has not been proven and it is therefore not recommended during pregnancy. Animal studies have not demonstrated teratogenic effects on the fetus. 
Lactating mother : Domperidone may precipitate galactorrhea and improve post-natal location. It is secreted in breast milk but in very small quantities insufficient to be considered harmful. 

Domperidone should be used with absolute caution in case of children because there may be an increased risk of extra-pyramidal reactions in young children because of an incompletely developed blood-brain barrier. Since Domperidone is highly metabolized in liver, it should be used with caution in patient with hepatic impairment.

There are no reported cases of overdosage.