S O M A T E C

About Us

SOMATEC PHARMACEUTICALS LTD. is a fast growing pharmaceutical company in Bangladesh.

Contact Info

28/B, Segun Bagicha, Dhaka-1000, Bangladesh.

+880-02-9337667

+880-02-9357827

+880-02-8391480

info@somatecpharmabd.com

NYST

NYST (Nystatin) is a tetraene macrolide of polyene antifungal antibiotics. lt is used to prevent or treat superficial candidiasis of the mouth, oesophagus or intestinal tract, for vaginal candidiasis and cutaneous infection. Like othei polyenes, NYST (Nystatin) binds with a sterol moiety, primarily ergosterol, present in the membrane of sensitive fungi and form pores or channels. As a result, permeability of the membrane is increased and a variety of small molecules come out from the cell. Ultimately cell death occurs.

Brand Name

: NYST

Generic Name

: Nystatin

Therapeutic Class

: Antifungals & Antiamoebic

Indications

NYST (Nystatin) is an antifungal antibiotic active against a wide range of yeast and yeast like fungi including Candida albicans. It is used for the prevention and treatment of candidal infections of the oral cavity, oesophagus and intestinal  tract. It provides effective prophylaxis against oral candidiasis in those born of mothers with vaginal candidiasis. It is used for the prophylaxis of candidal overgrowth during course of broad-spectrum antibiotics.

Dosage

Adults: 
1-6 ml four times daily.
For the treatment of denture sores and oral infection on adults caused by C. albicans, 1-2 ml of the suspension should be dropped into the mouth four times daily; it should be kept in contact with the affected areas as long as possible. Older people with intestinal candidiasis may be given 5 ml of the suspension four times a day.
Children:
1-6 ml four times daily in children.
1-2 ml four times daily in infants.
In intestinal and oral candidiasis (thrush) in infants and children, 1-2 ml should be dropped into the mouth four times a day.
The longer the suspension is kept in contact with the affected area in the mouth before swallowing, the greater will be its effect.
For prophylaxis of oral candidiasis in the new born, the suggested dose is 1 ml once daily. Administration should be continued for 48 hours after clinical cure to prevent relapse.

Contraindications

It should not be used in those patients who are hypersensitive to Nystatin. There is no known contraindication to the use of Nystatin.

Side Effects

Nausea, vomiting and diarrhoea have occasionally been reported with high doses of Nystatin. No systemic etfects or allergic reaclions have been associated wlth its oral dose.

Precautions & Warnings

As absorption from the gastrointestinal tract is negligible, therefore no special precautions apply in pregnancy and lactation.

Indications

NYST (Nystatin) is an antifungal antibiotic active against a wide range of yeast and yeast like fungi including Candida albicans. It is used for the prevention and treatment of candidal infections of the oral cavity, oesophagus and intestinal  tract. It provides effective prophylaxis against oral candidiasis in those born of mothers with vaginal candidiasis. It is used for the prophylaxis of candidal overgrowth during course of broad-spectrum antibiotics.

Dosage

Adults: 
1-6 ml four times daily.
For the treatment of denture sores and oral infection on adults caused by C. albicans, 1-2 ml of the suspension should be dropped into the mouth four times daily; it should be kept in contact with the affected areas as long as possible. Older people with intestinal candidiasis may be given 5 ml of the suspension four times a day.
Children:
1-6 ml four times daily in children.
1-2 ml four times daily in infants.
In intestinal and oral candidiasis (thrush) in infants and children, 1-2 ml should be dropped into the mouth four times a day.
The longer the suspension is kept in contact with the affected area in the mouth before swallowing, the greater will be its effect.
For prophylaxis of oral candidiasis in the new born, the suggested dose is 1 ml once daily. Administration should be continued for 48 hours after clinical cure to prevent relapse.

Contraindications

It should not be used in those patients who are hypersensitive to Nystatin. There is no known contraindication to the use of Nystatin.

Side Effects

Nausea, vomiting and diarrhoea have occasionally been reported with high doses of Nystatin. No systemic etfects or allergic reaclions have been associated wlth its oral dose.

Precautions & Warnings

As absorption from the gastrointestinal tract is negligible, therefore no special precautions apply in pregnancy and lactation.

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