Indications

1) Diarrhoea caused by Giardia lamblia or Cryptosporidium parvum.
2) Amebiasis and helminth infections.

Dosage

Indication
Diarrhoea caused
by Giardia lamblia 
or Cryptosporidium parvum and Amebiasis and helminth infections.
Age

1-3 years

4-11 years

³ 12 years
Dosage
Suspension 5 ml
(1 teaspoonful) twice daily with food
Suspension 10 ml 
(2 teaspoonfuls) twice daily with food
1 tablet or 25 ml suspension 
(5 teaspoonfuls) twice daily with food
Duration

3 days

Interaction

Nitazoxanide is highly bound to plasma protein (>99.9%). Therefore, caution should be used when administering Nitazoxanide concurrently with other highly plasma protein-bound drugs with narrow therapeutic indices.

Contraindications

Nitazoxanide is contraindicated in patients with a prior hypersensitivity to Nitazoxanide or any other ingredient in this formulations.

Side Effects

Nitazoxanide is generally well tolerated. However abdominal pain, diarrhoea, vomiting and headache have been reported rarely.

Pregnancy & Lactation

Pregnancy Category B: This drug should be used during pregnancy only if clearly needed.
Nursing Mothers: It is not known whether Nitazoxanide is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Nitazoxanide is administered to a nursing woman.

Overdose Effects

Information on Nitazoxanide overdosage is not available. Single oral doses of up to 4,000 mg Nitazoxanide have been administered to healthy adult volunteers without significant adverse effects. In the event of overdose, gastric lavage may be performed. Patients should be carefully observed and given symptomatic and supportive treatment.

Storage Conditions

· Store in cool and dry place, protect from light.· Keep out of reach of children· Once reconstituted, suspension should be used within 7 days.