S O M A T E C

About Us

SOMATEC PHARMACEUTICALS LTD. is a fast growing pharmaceutical company in Bangladesh.

Contact Info

28/B, Segun Bagicha, Dhaka-1000, Bangladesh.

+880-02-9337667

+880-02-9357827

+880-02-8391480

info@somatecpharmabd.com

Tifen

Tifen Tablet : Each tablet contains Ketotifen Fumarate BP 1.38 mg  equivalent to Ketotifen 1 mg.
Tifen Syrup : Each 5 ml syrup contains Ketotifen Fumarate BP 1.38 mg
equivalent to Ketotifen 1 mg.

Brand Name

: Tifen

Generic Name

: Ketotifen BP

Therapeutic Class

: Antiasthmatic & Antihistamines

Strength

:
1mg 100ml

Indications

Tifen is indicated for the following conditions-
1. For the prophylactic treatment of bronchial asthma.
2. Symptomatic treatment of allergic conditions including rhinitis and
   conjunctivitis.
3. For alleviating the complications of itching, pain and tenderness
   associated with neurofibroma.
4. Symptomatic treatment of allergy such as hayfever, urticaria.

Dosage

Adult: 1 mg twice daiIy with food. The dose may be increased to 2 mg twice daily in severe cases, if necessary.
Children above 2 years: 1 mg twice daily with food.
Use in the elderly: same as adult dose.
N.B. Patients known to be easily sedated should begin treatment with 0.5 mg to 1 mg at night for the first few days.

Interaction

Tifen may potentiate the effects of sedatives, hypnotics, antihistamines and alcohols. A reversible fall in the platelet count has been observed in a few patients receiving Tifen concomitantly with oral antidiabetic agents and it has been suggested that this combination should therefore be avoided.

Contraindications

Although there is no evidence of any teratogenic effect, recommendations for Tifen in pregnancy or when breast feeding cannot be given.

Side Effects

Drowsiness, dry mouth and slight dizziness may occur at the beginning of treatment, but usually disappear spontaneously after a few days.

Precautions & Warnings

It is important to continue the previous treatment for a minimum of two weeks after starting Tifen to avoid the possibility of exacerbation of asthma. This applies specially to systemic corticosteroids and ACTH because of the possible existence of adrenocortical insufficiency in steroid dependent patient. If intercurrent infection occurs, Tifen treatment must be supplemented by specific antimicrobial therapy. During the first days of treatment with Tifen, reactions may be impaired and patient should be warned not to take charge of vehicle or machinery until the effect of Tifen treatment on the individual is known. Patient should be advised to avoid alcoholic drinks.

Overdose Effects

The reported feature of over doses include confusion, drowsiness, nystagmus, headache and disorientation. Bradycardia and respiratory depression should be watched for. Elimination of the drug with gastric lavage or emesis is recommended. Otherwise, general supportive treatment that is required should be instituted.

Storage Conditions

·  Store in cool & dry place, protected from light.
·  Keep out of reach of children.

Indications

Tifen is indicated for the following conditions-
1. For the prophylactic treatment of bronchial asthma.
2. Symptomatic treatment of allergic conditions including rhinitis and
   conjunctivitis.
3. For alleviating the complications of itching, pain and tenderness
   associated with neurofibroma.
4. Symptomatic treatment of allergy such as hayfever, urticaria.

Dosage

Adult: 1 mg twice daiIy with food. The dose may be increased to 2 mg twice daily in severe cases, if necessary.
Children above 2 years: 1 mg twice daily with food.
Use in the elderly: same as adult dose.
N.B. Patients known to be easily sedated should begin treatment with 0.5 mg to 1 mg at night for the first few days.

Interaction

Tifen may potentiate the effects of sedatives, hypnotics, antihistamines and alcohols. A reversible fall in the platelet count has been observed in a few patients receiving Tifen concomitantly with oral antidiabetic agents and it has been suggested that this combination should therefore be avoided.

Contraindications

Although there is no evidence of any teratogenic effect, recommendations for Tifen in pregnancy or when breast feeding cannot be given.

Side Effects

Drowsiness, dry mouth and slight dizziness may occur at the beginning of treatment, but usually disappear spontaneously after a few days.

Precautions & Warnings

It is important to continue the previous treatment for a minimum of two weeks after starting Tifen to avoid the possibility of exacerbation of asthma. This applies specially to systemic corticosteroids and ACTH because of the possible existence of adrenocortical insufficiency in steroid dependent patient. If intercurrent infection occurs, Tifen treatment must be supplemented by specific antimicrobial therapy. During the first days of treatment with Tifen, reactions may be impaired and patient should be warned not to take charge of vehicle or machinery until the effect of Tifen treatment on the individual is known. Patient should be advised to avoid alcoholic drinks.

Overdose Effects

The reported feature of over doses include confusion, drowsiness, nystagmus, headache and disorientation. Bradycardia and respiratory depression should be watched for. Elimination of the drug with gastric lavage or emesis is recommended. Otherwise, general supportive treatment that is required should be instituted.

Storage Conditions

·  Store in cool & dry place, protected from light.
·  Keep out of reach of children.

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