Mucobrox is a preparation of Ambroxol Hydrochloride. Ambroxol has secretomotor with secretolytic effects. It stimulates serous cells of bronchial mucous membranes, increases mucous secretion content by changing the structure of bronchial secretion. Thus results in reduction of expectoration viscosity by reducing and fragmenting mucopolysaccharide fibers. It also intensifies motion of ciliated epithelium cilia, increasing expectoration transport. Ambroxol stimulates synthesis of phospholipids by alveolar cells and formation of surfactant lipids. It clearly improves breathing and suppresses coughing to some extent.
Mucobrox Syrup : Each 5 ml of syrup contains Ambroxol Hydrochloride BP 15 mg.
Mucobrox Paediatric Drops: Each ml of drop contains Ambroxol Hydrochloride BP 6 mg.
Mucobrox is indicated in acute and chronic infections of the respiratory tract associated with abnormal secretions, such as-
¨Acute exacerbations of chronic bronchitis
Inflammatory diseases of the rhino pharyngeal tract, like-
Dosage and Administration:
Mucobrox is recommended to be administered after meal.
Mucobrox Paediatric Drops:
0-6 months old… 0.5 ml; 2 times a day
6-12 months old… 1 ml; 2 times a day
1-2 years old… 1.25 ml; 2 times a day
2-5 years old…2.5 ml (1/2 teaspoonful); 2-3 times a day
5-10 years old… 5 ml, (1 teaspoonful); 2-3 times a day
10 years old and adults…10 ml (2 teaspoonfuls); 3 times a day
Mucobrox is contraindicated in patients who are sensitive to Ambroxol Hydrochloride or Bromhexine.
Use in Pregnancy and Lactation:
Safety of Ambroxol in pregnancy has not yet been established. It is not recommended in pregnancy, especially during the first trimester. Safety during lactation has not yet been established.
If there is any problem related to kidney, renal insufficiency or liver, consultation with the prescriber is needed. Patients with gastric-duodenal ulceration & convulsive disorders should take the drug cautiously.
Mucobrox is well tolerated, however, rarely allergic responses such as skin eruption, urticaria or angioneurotic edema may occur. While used for a long time, gastrointestinal side effects like epigastric pain, stomach overfill feeling cannot be excluded.
Keep away from light, store in a cool (below 30OC) and dry place. Keep out of reach of children.
Mucobrox Syrup: Bottle containing 100 ml syrup.
Mucobrox Paediatric drops : Bottle containing 15 ml paediatric drops.