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Bromol (Levosalbutamol)

Description:

Levosalbutamol is a single isomer beta2 agonist that differs from racemic salbutamol by elimination of (S)-salbutamol. Levosalbutamol is an effective bronchodilator whose primary mechanism of action is unimpeded by (S)-salbutamoI. Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved with doses that substantially lessen beta-mediated side effects. Levosalbutamol produces bronchodilatation through stimulation of beta2-adrenergic receptors in bronchial smooth muscles, thereby causing relaxation of bronchial muscle fibres.

Composition:

Bromol 1 tablet : Each tablet contains Levosalbutamol Sulphate INN equivalent to Levosalbutamol 1.0 mg.

Bromol 2 tablet : Each tablet contains Levosalbutamol Sulphate INN equivalent to Levosalbutamol 2.0 mg.

Bromol Syrup : Each 5 ml syrup contains Levosalbutamol Sulphate INN equivalent to Levosalbutamol 1.0 mg.

Indication:

Levosalbutamol is indicated for the treatment and prevention of bronchospasm in adults, adolescents and children 6 years of age and older with reversible obstructive airway diseases.

osage and Administration:

Adults and adolescents above 12 years- 1-2 mg, three times daily.

Children (6 -11 years)- 1 mg, three times daily.

Side Effect:

Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, burning substernal or epigastric.

Precaution:

Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations. pain and diarrhoea.

Use in Pregnancy and Lactation:

Pregnancy

The drug should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. Lactation

It is not known whether levosalbutamol is excreted in human milk. Caution should be exercised when oral levosalbutamol is administered to a nursing woman.

Contraindication:

Levosalbutamol is contraindicated in patients with a history of hypersensitivity to Levosalbutamol or any of its components.

Drug Interaction:

Other short-acting sympathomimetic bronchodilators or epinephrine should be used with caution with Levosalbutamol. If additional adrenergic drugs are to be administered by any route, they should be used with caution to avoid deleterious cardiovascular effects.

Overdose:

The expected symptoms with over dosage are those of excessive beta-adrenergic stimulation and the symptoms listed under side effects. In the event of serious poisoning, the stomach should be emptied and, if necessary, a beta-blocker should be administered with caution in patients with a history of bronchospasm.

Packaging:

Bromol 1 tablet : Each box contains 10x10's tablet in blister pack.

Bromol 2 tablet : Each box contains 10x10's tablet in blister pack.

Bromol Syrup: Each bottle contains 100 ml syrup of Levosalbutamol.

 

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