Zodin (Ranitidine Hydrochloride) is a competitive, reversible
inhibitor of the action of histamine H2 receptors, including receptors on the gastric cells. As a result of its H2 receptor blocking action Zodin promotes rapid and effective ulcer healing with sustained pain relief, both day and night by a reduction in gastric acid output.
Zodin Tablet : Each film coated tablet contains Ranitidine Hydrochloride USP equivalent to 150 mg of Ranitidine USP.
Zodin Syrup : Each 5 ml Syrup contains Ranitidine Hydrochloride USP equivalent to 75 mg of Ranitidine USP.
1. Gastric & Duodenal Ulcer
2. Gastro Esophageal Reflux Disease
3. Zollinger-Ellison Syndrome
4. Erosive Oesophagitis
5. Pathological Hypersecretory Conditions
6. Chronic Episodic Dyspepsia
7. NSAIDs Induced Ulcer
Dosage and administration:
By mouth: Twice daily for 4 to 8 weeks.
Duodenal ulcer : Twice daily; 2 tablets at night for 4 to 8 weeks.
Maintenance dose: 1 Tablet at night.
By mouth: 2 tea-spoonfuls twice daily for 4 to 8 weeks.
Duodenal ulcer : 2 tea-spoonfuls twice daily; 4 tea spoonfuls at
night for 4 to 8 weeks.
Maintenance dose: 2 tea-spoonfuls at night.
Child: Peptic ulcer: 2-4 mg/kg twice daily. Maximun 4 tea
Reflux Oesophagitis : 2 tea-spoonfuls twice daily or 4 tea-
spoonfuls at night for upto 8 weeks.
Zollinger-Ellison Syndrome: 2 tea-spoonfuls 3 times daily.
Gastric acid reduction: 2 tea-spoonfuls at night time.
Ranitidine may cause reversible confusion, headache, malaise, constipation, diarrhoea, increased SGPT, hepatitis, anaphylactic reactions, thrombocytopenia, leucopenia. It may also cause rarely tachycardia, bradycardia, atrioventricular block and premature ventricular beats.
Ranitidine should be used with caution in patients with impaired renal function and hepatic dysfunction.
Pregnancy and Lactation:
It should be used during pregnancy only if clearly needed. As Ranitidine is secreted in human milk caution should be exercised when it is administered to a nursing mother.
Recommended doses of Zodin do not inhibit the action of the Cytochrome P-450 linked oxygenase enzymes in the liver. It has no effect on warfarin clearance or prothrombin time.
Zodin Tablet : Each Box contains 10 x 10 tablets in blister pack.
Zodin Syrup : Each Bottle contains 100 ml Syrup.