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TYDIN (Cephradine)

COMPOSITION:

TYDIN 250 capsule : Each capsule contains Cephradine BP 250 mg.

TYDIN 500 capsule : Each capsule contains Cephradine BP 500 mg.

TYDIN Powder for Suspension : When reconstituted each 5ml suspension contains Cephradine BP 125 mg.

TYDIN DS Powder for Suspension : When reconstituted each 5 ml suspension contains Cephradine BP 250 mg.

TYDIN Paediatric drops : When reconstituted each 1.25 ml contains Cephradine BP 125 mg.

INDICATION:

Cephradine is indicated in the treatment of following infections caused by sensitive organisms:

Upper respiratory tract infections : Pharyngitis, Sinusitis, Otitis media, Tonsillitis, Laryngo-tracheo bronchitis.

Lower respiratory tract infections : Acute & chronic bronchitis, Lobar and Bronchopneumonia.

Urinary tract infections : Cystitis, Urethritis, Pyelonephritis, Bacteriuria.

Skin and soft tissue infections : Abscess, Cellulitis, Furunculosis, Impetigo.

Gastrointestinal tract infections : Bacillary dysentery, Enteritis, Peritonitis.

As surgical prophylaxis.

DOSAGE AND ADMINISTRATION:

Adult : 250-500 mg every 6 hours or 0.5-1 g every 12 hours.

Child : 25-50 mg/kg daily in divided doses.

CONTRAINDICATION :

It should not be used in those patients who are hypersensitive to cephalosporin antibiotic

PRECAUTION:

Cephradine should be used with caution in those patients who are hypersensitive to penicillins..

SIDE EFFECT:

Adverse effects include nausea, vomiting, diarrhoea and abdominal discomfort. Allergic reactions include skin rashes, urticaria, eosinophilia, angioedema and anaphylaxis may occur and rise in liver enzyme values have been noted. Neutropenia has been reported. There is the possibility of development of pseudomembranous colitis.

INFORMATION TO PATIENT:

Capsule : Patients should be cautioned that TYDIN capsule should not be opened, chewed or crushed and should be swallowed whole.

Dry suspension and Paediatric drops: The reconstituted suspension must be used within 7 days if kept at room temperature and within 10 days when stored in a refrigerator. The preparation should be kept in a cool, dry place and away from children.

PACKAGING:

TYDIN 250 capsule : Box containing 5x4's capsules in Alu-Alu pack.

TYDIN 500 capsule : Box containing 5x4's capsules in Alu-Alu pack.

TYDIN Powder for Suspension : Bottle containing powder to produce 100 ml of suspension when reconstituted.

TYDIN DS Powder for Suspension : Bottle containing powder to produce 100 ml of suspension when reconstituted.

TYDIN Paediatric drops : Bottle containing powder to produce 15 ml drops when reconstituted.

 

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